WHAT DOES PKRRATING MEAN?

The interfacial residues are remarkably conserved among eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements show which the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations support a design where by activating RNA serves as being a scaffold to bind a number of PKR monomers, es

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